PyMethylProcess

convenient high-throughput preprocessing workflow for DNA methylation data

pymethylprocess_overview

https://github.com/Christensen-Lab-Dartmouth/PyMethylProcess

Wiki: https://github.com/Christensen-Lab-Dartmouth/PyMethylProcess/wiki

Help documentation: https://christensen-lab-dartmouth.github.io/PyMethylProcess/

Alternatively, you can access the pdf: PyMethylProcess.pdf

What is it:

  • Preprocess 450k and 850k methylation IDAT files in parallel using Minfi, ENmix, and meffil
  • Convenient and scalable implementation
  • Imputation and Feature Selection
  • Preparation for machine learning pipelines

Why:

  • Make DNAm accessible to python developers and more machine learning oriented researchers
  • Streamlined analysis makes processing easy

PyMethyProcess is now available in Bioinformatics: https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btz594/5542385 .